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1 Alkyl 2 acetylglycerophosphocholine Esterase

A Lipoprotein-associated Phospholipase A2 which modulates the action of Platelet Activating Factor by hydrolyzing the SN-2 ester bond to yield the biologically inactive lyso-Platelet-activating factor. It has specificity for phospholipid substrates with short-chain residues at the SN-2 position, but inactive against long-chain Phospholipids. Deficiency in this enzyme is associated with many Diseases including Asthma, and Hypercholesterolemia.