3 alpha-Hydroxysteroid Dehydrogenase (B-Specific)

A 3-hydroxysteroid Dehydrogenase which catalyzes the reversible reduction of the active androgen, Dihydrotestosterone to 5 ALPHA-ANDROSTANE-3 ALPHA,17 BETA-DIOL. It also has activity towards other 3-alpha-Hydroxysteroids and on 9-, 11- and 15- hydroxyprostaglandins. The enzyme is B-specific in reference to the Orientation of reduced NAD or NADPH.