4 1BB Receptors

A member of the Tumor Necrosis Factor Receptor superfamily that is specific for 4-1BB Ligand. It is found in a variety of immune Cell types including activated T-Lymphocytes; Natural Killer Cells; and Dendritic Cells. Activation of the receptor on T-Lymphocytes plays a Role in their expansion, production of Cytokines and Survival. Signaling by the activated receptor occurs through its Association with TNF Receptor-Associated Factors.