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5 HT Uptake Inhibitors

Compounds that specifically inhibit the reuptake of Serotonin in the Brain. This increases the Serotonin concentration in the synaptic cleft which then activates Serotonin Receptors to a greater extent. These agents have been used in treatment of Depression, Panic Disorder, Obsessive-Compulsive Behavior, and Alcoholism, as Analgesics, and to treat Obesity and Bulimia. Many of the Adrenergic Uptake Inhibitors also inhibit Serotonin uptake; they are not included here.