Email

6-Phosphofructokinase, Muscle Type

An allosteric enzyme that regulates Glycolysis by catalyzing the Transfer of a phosphate group from ATP to Fructose-6-phosphate to yield Fructose-1,6-bisphosphate. In Humans, Phosphofructokinase-1 in Muscle exists as the homotetramer of M subunits. Defects in this Muscle enzyme cause Glycogen Storage Disease Type VII, also known as Tarui's Disease.