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Acetohydroxy Acid Isomeroreductase

An enzyme that catalyzes the oxidation of (R)-2,3-dihydroxy-3-methylbutanoate to (S)-2-hydroxy-2-methyl-3-oxobutanoate in the presence of NADP. It is involved in the biosynthesis of Valine; Leucine; Isoleucine; pentothenate and COENZYME A. This enzyme was formerly classified as EC 1.1.1.89.