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Acid, Aureolic

A tricyclic pentaglycosidic antibiotic from Streptomyces strains that inhibits RNA and protein synthesis by adhering to DNA. It is used as a fluorescent dye and as an antineoplastic agent, especially in bone and Testicular Tumors. Plicamycin is also used to reduce Hypercalcemia, especially that due to malignancies.