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Acids, Clavulanic

Acids, Salts, and derivatives of Clavulanic Acid (C8H9O5N). They consist of those beta-lactam compounds that differ from penicillin in having the Sulfur of the thiazolidine ring replaced by an Oxygen. They have limited antibacterial action, but block bacterial beta-Lactamase irreversibly, so that similar Antibiotics are not broken down by the bacterial Enzymes and therefore can exert their antibacterial effects.