Activating Transcription Factors

Activating Transcription Factors were originally identified as DNA-Binding Proteins that interact with early promoters from Adenoviruses. They are a Family of Basic Leucine Zipper Transcription Factors that bind to the Consensus site TGACGTCA of the Cyclic AMP Response Element, and are closely related to Cyclic AMP-Responsive DNA-Binding Protein.