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Activation, Lymphocyte

Morphologic alteration of small B Lymphocytes or T Lymphocytes in Culture into large blast-like Cells able to synthesize DNA and RNA and to divide mitotically. It is induced by Interleukins; Mitogens such as Phytohemagglutinins, and by specific Antigens. It may also occur in vivo as in Graft Rejection.