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Activator, NF-KappaB Receptor

A Tumor Necrosis Factor Receptor Family member that is specific for RANK Ligand and plays a Role in bone Homeostasis by regulating osteoclastogenesis. It is also expressed on Dendritic Cells where it plays a Role in regulating Dendritic Cell Survival. Signaling by the activated receptor occurs through its Association with TNF Receptor-Associated Factors.