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Adrenal Hyperplasias, Congenital

A group of inherited disorders of the Adrenal Glands, caused by enzyme defects in the synthesis of Cortisol (Hydrocortisone) and/or Aldosterone leading to accumulation of precursors for Androgens. Depending on the Hormone imbalance, congenital adrenal Hyperplasia can be classified as salt-wasting, hypertensive, virilizing, or feminizing. Defects in Steroid 21-Hydroxylase; Steroid 11-beta-Hydroxylase; Steroid 17-alpha-Hydroxylase; 3-beta-Hydroxysteroid Dehydrogenase (3-Hydroxysteroid Dehydrogenases); Testosterone 5-alpha-Reductase; or steroidogenic acute regulatory protein; among others, underlie these disorders.