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Agonist, Calcium Channel

Agents that increase Calcium influx into Calcium Channels of excitable Tissues. This causes Vasoconstriction in Vascular Smooth Muscle and/or Cardiac Muscle Cells as well as stimulation of Insulin release from Pancreatic Islets. Therefore, Tissue-selective Calcium agonists have the potential to combat Cardiac Failure and endocrinological disorders. They have been used primarily in experimental studies in Cell and Tissue Culture.