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Aldosterone Synthase Cytochrome P-450

A mitochondrial Cytochrome P450 enzyme that catalyzes the 18-Hydroxylation of Steroids in the presence of molecular Oxygen and NADPH-specific flavoprotein. This enzyme, encoded by CYP11B2 Gene, is important in the conversion of Corticosterone to 18-Hydroxycorticosterone and the subsequent conversion to Aldosterone.