alpha,25-Dihydroxyvitamin D3, 1

The physiologically active form of Vitamin D. It is formed primarily in the Kidney by enzymatic Hydroxylation of 25-Hydroxycholecalciferol (Calcifediol). Its production is stimulated by low Blood Calcium levels and Parathyroid Hormone. Calcitriol increases Intestinal Absorption of Calcium and Phosphorus, and in concert with Parathyroid Hormone increases Bone Resorption.