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alphav Integrin

An alpha integrin with a Molecular Weight of 160-kDa that is found in a variety of Cell types. It undergoes posttranslational cleavage into a heavy and a Light chain that are connected by disulfide bonds. Integrin alphaV can combine with several different beta subunits to form heterodimers that generally bind to RGD sequence-containing Extracellular Matrix Proteins.