Alu Elements
Synonyms
Alu Element
Alu Families
Alu Family
Alu Repetitive Sequence
Alu Repetitive Sequences
Alu-Like Repetitive Sequence
Element, Alu
Elements, Alu
Families, Alu
Family, Alu
Repetitive Sequence, Alu
Repetitive Sequences, Alu
Sequence, Alu Repetitive
Sequences, Alu Repetitive
The Alu sequence family (named for the restriction endonuclease cleavage enzyme Alu I) is the most highly repeated interspersed repeat element in humans (over a million copies). It is derived from the 7SL RNA component of the SIGNAL RECOGNITION PARTICLE and contains an RNA polymerase III promoter. Transposition of this element into coding and regulatory regions of genes is responsible for many heritable diseases.
See Also