Aminopeptidase, Cytosol

A Zinc containing enzyme of the hydrolase class that catalyzes the removal of the N-terminal amino acid from most L-Peptides, particularly those with N-terminal Leucine residues but not those with N-terminal Lysine or Arginine residues. This occurs in Tissue Cell Cytosol, with high activity in the Duodenum, liver, and Kidney. The activity of this enzyme is commonly assayed using a Leucine arylamide chromogenic substrate such as leucyl beta-naphthylamide.