An enzyme that catalyzes the conversion of L-Tyrosine and 2-oxoglutarate to 4-hydroxyphenylpyruvate and L-GLUTAMATE. It is a Pyridoxal-phosphate protein. L-Phenylalanine is hydroxylated to L-Tyrosine. The mitochondrial enzyme may be identical with Aspartate Aminotransferases (EC 22.214.171.124.). Deficiency of this enzyme may cause type II Tyrosinemia (see Tyrosinemias). EC 126.96.36.199.