Amplified in Breast Cancer 1 Protein

A nuclear receptor coactivator with specificity for Estrogen Receptors and Progesterone Receptors. It contains a Histone Acetyltransferase activity that may play a Role in Chromatin Remodeling during the process of nuclear receptor-induced transcription. The coactivator has been found at elevated levels in certain Hormone-Dependent Neoplasms such as those found in Breast CANCER.