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Amyloid Polyneuropathy

Disorders of the Peripheral Nervous System associated with the deposition of Amyloid in nerve Tissue. Familial, primary (nonfamilial), and secondary Forms have been described. Some familial subtypes demonstrate an autosomal dominant pattern of inheritance. Clinical manifestations include sensory loss, mild weakness, autonomic dysfunction, and Carpal Tunnel Syndrome. (Adams et al., Principles of Neurology, 6th ed, p1349)