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Amyloid Polypeptide, Islet

A pancreatic beta-Cell Hormone that is co-secreted with Insulin. It displays an anorectic effect on nutrient Metabolism by inhibiting Gastric Acid Secretion, Gastric Emptying and postprandial Glucagon Secretion. Islet Amyloid polypeptide can fold into Amyloid FIBRILS that have been found as a major constituent of pancreatic Amyloid Deposits.