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Angiotensin-(1-8) Octapeptide

An octapeptide that is a potent but labile vasoconstrictor. It is produced from Angiotensin I after the removal of two Amino Acids at the C-terminal by Angiotensin Converting Enzyme. The amino acid in position 5 varies in different species. To block Vasoconstriction and Hypertension effect of Angiotensin II, Patients are often treated with ACE Inhibitors or with Angiotensin II Type 1 Receptor Blockers.