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Angiotensin I Converting Enzyme Inhibitors

A class of Drugs whose main indications are the treatment of Hypertension and Heart Failure. They exert their Hemodynamic effect mainly by inhibiting the Renin-Angiotensin System. They also modulate Sympathetic Nervous System activity and increase prostaglandin synthesis. They cause mainly Vasodilation and mild Natriuresis without affecting Heart Rate and contractility.