Antibodies, Antineutrophil Cytoplasmic

Synonyms

ANCA

Anti Neutrophil Cytoplasmic Antibodies

Anti Neutrophil Cytoplasmic Antibody

Anti-Neutrophil Cytoplasmic Antibodies

Anti-Neutrophil Cytoplasmic Antibody

Antibodies, Anti-Neutrophil Cytoplasmic

Antibody, Anti-Neutrophil Cytoplasmic

Antibody, Antineutrophil Cytoplasmic

Antineutrophil Cytoplasmic Antibodies

Antineutrophil Cytoplasmic Antibody

Cytoplasmic Antibodies, Anti-Neutrophil

Cytoplasmic Antibodies, Antineutrophil

Cytoplasmic Antibody, Anti-Neutrophil

Cytoplasmic Antibody, Antineutrophil

c ANCA

c-ANCA

p ANCA

p-ANCA

Autoantibodies directed against cytoplasmic constituents of POLYMORPHONUCLEAR LEUKOCYTES and/or MONOCYTES. They are used as specific markers for GRANULOMATOSIS WITH POLYANGIITIS and other diseases, though their pathophysiological role is not clear. ANCA are routinely detected by indirect immunofluorescence with three different patterns: c-ANCA (cytoplasmic), p-ANCA (perinuclear), and atypical ANCA.