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Antibodies, Antinuclear

Autoantibodies directed against various Nuclear Antigens including DNA, RNA, Histones, acidic Nuclear Proteins, or complexes of these molecular Elements. Antinuclear Antibodies are found in systemic Autoimmune Diseases including Systemic Lupus Erythematosus, Sjogren's Syndrome, scleroderma, Polymyositis, and Mixed Connective Tissue Disease.