Antibody-Dependent Cell Cytotoxicity

Synonyms

ADCC

Antibody Dependent Cell Cytotoxicity

Antibody-Dependent Cell Cytotoxicities

Antibody-Dependent Cell Cytoxicities

Antibody-Dependent Cell Cytoxicity

Cell Cytotoxicities, Antibody-Dependent

Cell Cytotoxicity, Antibody-Dependent

Cell Cytoxicities, Antibody-Dependent

Cell Cytoxicity, Antibody Dependent

Cell Cytoxicity, Antibody-Dependent

Cytotoxicities, Antibody-Dependent Cell

Cytotoxicity, Antibody Dependent Cell

Cytotoxicity, Antibody-Dependent Cell

Cytoxicities, Antibody-Dependent Cell

Cytoxicity, Antibody-Dependent Cell

The phenomenon of antibody-mediated target cell destruction by non-sensitized effector cells. The identity of the target cell varies, but it must possess surface IMMUNOGLOBULIN G whose Fc portion is intact. The effector cell is a "killer" cell possessing Fc receptors. It may be a lymphocyte lacking conventional B- or T-cell markers, or a monocyte, macrophage, or polynuclear leukocyte, depending on the identity of the target cell. The reaction is complement-independent.