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Antibody-Dependent Enhancements

Enhancement of viral infectivity caused by non-Neutralizing Antibodies. There are at least two mechanisms known to account for this: Mediation by Fc Receptors (Receptors, Fc) or by Complement Receptors (Receptors, Complement). Either the Virus is complexed with antiviral Immunoglobulin G and binds to Fc Receptors, or Virus is coated with antiviral Immunoglobulin M and binds to Complement Receptors.