Antigens, CD120a

A Tumor Necrosis Factor Receptor subtype that has specificity for Tumor Necrosis Factor alpha and Lymphotoxin alpha. It is constitutively expressed in most Tissues and is a key mediator of Tumor Necrosis Factor signaling in the vast majority of Cells. The activated receptor signals via a conserved Death domain that associates with specific TNF Receptor-Associated Factors in the Cytoplasm.