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Antigens, CD137

A member of the Tumor Necrosis Factor Receptor superfamily that is specific for 4-1BB Ligand. It is found in a variety of immune Cell types including activated T-Lymphocytes; Natural Killer Cells; and Dendritic Cells. Activation of the receptor on T-Lymphocytes plays a Role in their expansion, production of Cytokines and Survival. Signaling by the activated receptor occurs through its Association with TNF Receptor-Associated Factors.