APO 1 Antigen

A Tumor Necrosis Factor Receptor subtype found in a variety of Tissues and on activated Lymphocytes. It has specificity for Fas Ligand and plays a Role in Regulation of peripheral immune responses and Apoptosis. Multiple Isoforms of the protein exist due to multiple Alternative Splicing. The activated receptor signals via a conserved Death domain that associates with specific TNF Receptor-Associated Factors in the Cytoplasm.