Apolipoprotein C-II

Synonyms

Apo C II

Apo C-II

ApoC2

Apolipoprotein C 2

Apolipoprotein C II

Apolipoprotein C-2

Apolipoprotein CII

Apoprotein C II

Apoprotein C-II

A 9-kDa protein component of VERY-LOW-DENSITY LIPOPROTEINS. It contains a cofactor for LIPOPROTEIN LIPASE and activates several triacylglycerol lipases. The association of Apo C-II with plasma CHYLOMICRONS; VLDL, and HIGH-DENSITY LIPOPROTEINS is reversible and changes rapidly as a function of triglyceride metabolism. Clinically, Apo C-II deficiency is similar to lipoprotein lipase deficiency (HYPERLIPOPROTEINEMIA TYPE I) and is therefore called hyperlipoproteinemia type IB.