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Arachidonic Acid 12 Lipoxygenase

An enzyme that catalyzes the oxidation of Arachidonic Acid to yield 12-hydroperoxyarachidonate (12-HPETE) which is itself rapidly converted by a Peroxidase to 12-hydroxy-5,8,10,14-eicosatetraenoate (12-HETE). The 12-hydroperoxides are preferentially formed in Platelets.