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Arachidonic Acid 5 Lipoxygenase

An enzyme that catalyzes the oxidation of Arachidonic Acid to yield 5-hydroperoxyarachidonate (5-HPETE) which is rapidly converted by a Peroxidase to 5-hydroxy-6,8,11,14-eicosatetraenoate (5-HETE). The 5-hydroperoxides are preferentially formed in Leukocytes.