Argininosuccinate Synthase
Synonyms
Argininosuccinate Synthetase
L-Citrulline:L-aspartate ligase (AMP-forming)
Synthase, Argininosuccinate
Synthetase, Argininosuccinate
An enzyme of the urea cycle that catalyzes the formation of argininosuccinic acid from citrulline and aspartic acid in the presence of ATP. Absence or deficiency of this enzyme causes the metabolic disease CITRULLINEMIA in humans. EC 6.3.4.5.
See Also