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c erbB 1 Protein

A Cell surface receptor involved in Regulation of Cell Growth and differentiation. It is specific for Epidermal Growth Factor and EGF related Peptides including Transforming Growth Factor alpha, amphiregulin, and Heparin-binding EGF-like Growth factor. The binding of ligand to the receptor causes activation of its intrinsic Tyrosine Kinase activity and rapid internalization of the receptor-ligand complex into the Cell.