Calpain
Synonyms
Ca2+ Activated Protease
Ca2+-Activated Protease
Calcium Activated Neutral Protease
Calcium Activated Neutral Proteinase
Calcium Activated Protease
Calcium Dependent Neutral Protease
Calcium Dependent Neutral Proteinase
Calcium-Activated Neutral Protease
Calcium-Activated Neutral Proteinase
Calcium-Activated Protease
Calcium-Dependent Neutral Protease
Calcium-Dependent Neutral Proteinase
Calpain I
Calpain II
Desminase
Neutral Protease, Calcium-Activated
Neutral Protease, Calcium-Dependent
Neutral Proteinase, Calcium-Activated
Neutral Proteinase, Calcium-Dependent
Protease, Ca2+-Activated
Protease, Calcium-Activated
Protease, Calcium-Activated Neutral
Protease, Calcium-Dependent Neutral
Proteinase, Calcium-Activated Neutral
Proteinase, Calcium-Dependent Neutral
Cysteine proteinase found in many tissues. Hydrolyzes a variety of endogenous proteins including NEUROPEPTIDES; CYTOSKELETAL PROTEINS; proteins from SMOOTH MUSCLE; CARDIAC MUSCLE; liver; platelets; and erythrocytes. Two subclasses having high and low calcium sensitivity are known. Removes Z-discs and M-lines from myofibrils. Activates phosphorylase kinase and cyclic nucleotide-independent protein kinase. This enzyme was formerly listed as EC 3.4.22.4.