Caspase 8
Synonyms
CAP4 Protease
Caspase-8
FLICE Protein
MACH Protein
Mch5 Protease
Pro Caspase 8
Pro-Caspase-8
Procaspase 8
Procaspase-8
A long pro-domain caspase that contains a death effector domain in its pro-domain region. Caspase 8 plays a role in APOPTOSIS by cleaving and activating EFFECTOR CASPASES. Activation of this enzyme can occur via the interaction of its N-terminal death effector domain with DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS.