Caspase 9
Synonyms
Apoptotic Protease Activating Factor 3
Caspase-9
ICE LAP6 Protein
ICE Like Apoptotic Protease 6
ICE-LAP6 Protein
ICE-Like Apoptotic Protease 6
Pro Caspase 9
Pro-Caspase-9
Procaspase 9
Procaspase-9
A long pro-domain caspase that contains a CASPASE RECRUITMENT DOMAIN in its pro-domain region. Caspase 9 is activated during cell stress by mitochondria-derived proapoptotic factors and by CARD SIGNALING ADAPTOR PROTEINS such as APOPTOTIC PROTEASE-ACTIVATING FACTOR 1. It activates APOPTOSIS by cleaving and activating EFFECTOR CASPASES.