Colistin

Synonyms

Colimycin

Colisticin

Colistin Sulfate

Coly-Mycin

Polymyxin E

Sulfate, Colistin

Totazina

Cyclic polypeptide antibiotic from Bacillus colistinus. It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. Colistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally.