Complement C5 Convertase, Classical Pathway

Synonyms

C5 Convertase (C4b2a3b)

C5 Convertase, Classical

Classical C5 Convertase

Classical Pathway C5 Convertase

A serine protease that cleaves multiple COMPLEMENT 5 into COMPLEMENT 5A (anaphylatoxin) and COMPLEMENT 5B in the CLASSICAL COMPLEMENT ACTIVATION PATHWAY. It is a complex of CLASSICAL PATHWAY C3 CONVERTASE (C4b2a) with an additional COMPLEMENT C3B, or C4b2a3b.