Core Binding Factor alpha Subunits

Synonyms

Acute Myeloid Leukemia Proteins

Core Binding Factor alpha Proteins

PEBP2A Transcription Factors

Polyomavirus Enhancer A Binding Protein 2

Polyomavirus Enhancer Binding Protein 2, Alpha Subunit

Runt Domain Factor

Runx Proteins

Transcription Factors, PEBP2A

A family of transcription factors that bind to the cofactor CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. Family members contain a highly conserved DNA-binding domain known as the runt domain. They can act as both activators and repressors of expression of GENES involved in CELL DIFFERENTIATION and CELL CYCLE progression.