Cytochrome P-450 CYP1A1

Synonyms

7-Ethoxyresorufin O-Deethylase

CYP 1A1

CYP1A1

CYP1A1 Protein

Cytochrome P 450 CYP1A1

Cytochrome P450 IA1

EROD

Ethoxyresorufin Dealkylase

Ethoxyresorufin O-Deethylase

Ethylresorufin O-Deethylase

A liver microsomal cytochrome P-450 monooxygenase capable of biotransforming xenobiotics such as polycyclic hydrocarbons and halogenated aromatic hydrocarbons into carcinogenic or mutagenic compounds. They have been found in mammals and fish. This enzyme, encoded by CYP1A1 gene, can be measured by using ethoxyresorufin as a substrate for the ethoxyresorufin O-deethylase activity.