Cytochrome P-450 CYP2D6
Synonyms
2-Hydroxylase, Imipramine
4-Hydroxylase, Debrisoquine
4-Monooxygenase, Debrisoquine
CYP 2D6
CYP2D6
CYP2D6, Cytochrome P-450
Cytochrome P 450 CYP2D6
Cytochrome P450 2D6
Debrisoquine 4 Hydroxylase
Debrisoquine 4 Monooxygenase
Debrisoquine 4-Hydroxylase
Debrisoquine 4-Monooxygenase
Debrisoquine Hydroxylase
Hydroxylase, Debrisoquine
Imipramine 2 Hydroxylase
Imipramine 2-Hydroxylase
Monooxygenase, Sparteine
P-450 CYP2D6, Cytochrome
P450 2D6, Cytochrome
Sparteine Monooxygenase
A cytochrome P450 enzyme that catalyzes the hydroxylation of many drugs and environmental chemicals, such as DEBRISOQUINE; ADRENERGIC RECEPTOR ANTAGONISTS; and TRICYCLIC ANTIDEPRESSANTS. This enzyme is deficient in up to 10 percent of the Caucasian population.