DAX-1 Orphan Nuclear Receptor

Synonyms

DAX 1 Orphan Nuclear Receptor

DSS AHC Critical Region on the X Chromosome, Gene 1 Protein

DSS-AHC Critical Region on the X Chromosome, Gene 1 Protein

NR0B1 Protein

Nuclear Receptor 0B1

Nuclear Receptor DAX 1

Nuclear Receptor DAX-1

Nuclear Receptor NR0B1

Nuclear Receptor Subfamily 0, Group B, Member 1

An orphan nuclear receptor that is implicated in regulation of steroidogenic pathways. It is unlike most orphan nuclear receptors in that it appears to lack an essential DNA-binding domain and instead acts as a transcriptional co-repressor. Mutations in the gene Dax-1 cause congenital adrenal hypoplasia.