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E 2 Kinase

A monomeric Calcium-Calmodulin-dependent Protein Kinase subtype that specifically phosphorylates Peptide Elongation Factor 2. The enzyme lacks a phosphorylatable activation domain that can respond to Calcium-Calmodulin-Dependent Protein Kinase Kinase, however it is regulated by Phosphorylation by Protein Kinase A and through intramolecular autoPhosphorylation.