Endothelin-1

Synonyms

Big Endothelin

Big Endothelin 1

Big Endothelin-1

Endothelin 1

Endothelin Type 1

Endothelin, Big

Endothelin-1, Big

Precursor, Proendothelin-1

Preproendothelin

Preproendothelin 1

Preproendothelin-1

Proendothelin (1-38)

Proendothelin 1 Precursor

Proendothelin-1 Precursor

A 21-amino acid peptide produced in a variety of tissues including endothelial and vascular smooth-muscle cells, neurons and astrocytes in the central nervous system, and endometrial cells. It acts as a modulator of vasomotor tone, cell proliferation, and hormone production. (N Eng J Med 1995;333(6):356-63)