Ephrin-A1
Synonyms
B61 Secreted Protein, Endothelium
EPLG1
Eck Ligand
Eck RPTK Ligand
Endothelium Secreted Protein B61
Ephrin A1
Epl1 Protein
LERK 1 Protein
LERK-1 Protein
Ligand, Eck
RPTK Ligand, Eck
An ephrin that was originally identified as the product of an early response gene induced by TUMOR NECROSIS FACTORS. It is linked to the CELL MEMBRANE via a GLYCOINOSITOL PHOSPHOLIPID MEMBRANE ANCHOR and binds EPHA2 RECEPTOR with high affinity. During embryogenesis high levels of ephrin-A1 are expressed in LUNG; KIDNEY; SALIVARY GLANDS; and INTESTINE.