Factor VIIIa

Synonyms

Activated Factor VIII

Blood Coagulation Factor VIII, Activated

Blood-coagulation factor VIIIa, procoagulant

Coagulation Factor VIIIa

Factor VIII, Activated

Factor VIII, Thrombin Activated

Factor VIII, Thrombin-Activated

Factor VIIIa Heavy Chain, 200 kDa Isoform

Factor VIIIa Heavy Chain, 92 kDa Isoform

Factor VIIIa Light Chain

Factor VIIIa, Coagulation

Thrombin-Activated Factor VIII

VIIIa, Coagulation Factor

Activated form of factor VIII. The B-domain of factor VIII is proteolytically cleaved by thrombin to form factor VIIIa. Factor VIIIa exists as a non-covalent dimer in a metal-linked (probably calcium) complex and functions as a cofactor in the enzymatic activation of factor X by factor IXa. Factor VIIIa is similar in structure and generation to factor Va.

See Also