Gangliosidoses, GM2
Synonyms
G(M2) Gangliosidoses
GM2 Gangliosidose
GM2 Gangliosidoses
GM2 Gangliosidosis
GM2, Gangliosidoses
Gangliosidose, GM2
Gangliosidoses GM2
Gangliosidosis, GM2
A group of recessively inherited diseases characterized by the intralysosomal accumulation of G(M2) GANGLIOSIDE in the neuronal cells. Subtypes include mutations of enzymes in the BETA-N-ACETYLHEXOSAMINIDASES system or G(M2) ACTIVATOR PROTEIN leading to disruption of normal degradation of GANGLIOSIDES, a subclass of ACIDIC GLYCOSPHINGOLIPIDS.
See Also